Kinetic Quantitation of Cerebral PET-FDG Studies Without Concurrent Blood Sampling: Statistical Recovery of the Arterial Input Function
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Metabolic liver function measured in vivo by dynamic 18F-FDGal PET/CT without arterial blood sampling
BACKGROUND Metabolic liver function can be measured by dynamic PET/CT with the radio-labelled galactose-analogue 2-[(18)F]fluoro-2-deoxy-D-galactose ((18)F-FDGal) in terms of hepatic systemic clearance of (18)F-FDGal (K, ml blood/ml liver tissue/min). The method requires arterial blood sampling from a radial artery (arterial input function), and the aim of this study was to develop a method for...
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BACKGROUND Quantification of kinetic parameters of positron emission tomography (PET) imaging agents normally requires collecting arterial blood samples which is inconvenient for patients and difficult to implement in routine clinical practice. The aim of this study was to investigate whether a population-based input function (POP-IF) reliant on only a few individual discrete samples allows acc...
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ژورنال
عنوان ژورنال: IEEE Transactions on Medical Imaging
سال: 2010
ISSN: 0278-0062,1558-254X
DOI: 10.1109/tmi.2009.2029096